Cellulose esters for pharmaceutical applications
Eastman understands the importance of patient compliance and offers different grades of cellulose esters to address varying performance and productivity requirements. Part of a family of cellulose derivatives with a long history in pharmaceutical applications, our cellulose esters form a semipermeable film membrane that can be laser drilled or used with pore formers for osmotic pump coatings and dosage forms. Our portfolio includes cellulose acetate (CA) and cellulose acetate butyrate (CAB) (cellaburate) to help achieve patient compliance by enabling extended/sustained release dosage forms.
- Our cellulose ester excipients are excellent film formers that enable zero-order release of a drug.
- Formulators dealing with a narrow/tight therapeutic index can formulate an osmotic pump dosage form using Eastman cellulose esters.
- Our cellulose acetate phthalate polymer is a well-known enteric coating polymer excipient that enables enteric and delayed release of a drug.
- Cellulose acetate phthalate can also be used as a protective/taste-masking coating that keeps the drug from being released in the acidic stomach environment.
- Blends of cellulose acetate phthalate and either CA or CAB can be used to formulate tablet coatings display a wide range of dissolution profiles.
Given customer input of how much drug is to be delivered over time, starting formulations can be predicted using Eastman’s unique algorithms.
To learn more about cellulose esters for pharmaceutical drug delivery, see our
brochures in the "Resources" section.
To access Eastman’s full portfolio, visit our
cellulose esters web pages.