Cedroz mode of action

What are root-knot nematodes?

According to the Merriam-Webster Dictionary, root-knot nematodes are small, plant-parasitic nematodes (genus Meloidogyne) that cause root knot. Mostly found in areas with warm climates or short winters, root-knot nematodes are found in all agricultural regions worldwide and can affect hundreds of different plant species. Their larvae infect plant roots, causing the development of root-knot galls that drain the plant’s photosynthate and nutrients. Severe infection in mature plants results in reduced yields, while infection in juvenile plants can be lethal.

Life cycle of the root-knot nematode

Life cycle of the root not nematode

Zeck scale to evaluate root damage

Zeck Scale to evaluate root damage

What are the active compounds in Cedroz?

Cedroz is a suspension of capsules in aqueous solution (CS) containing a mixture of two active compounds—the monoterpenes thymol and geraniol.

Cedroz active compounds



How does Cedroz work against root-knot nematodes?

The active compounds thymol and geraniol act against nematodes through different mechanisms. Thanks to their lipophilic nature, they can accumulate in the cell membranes of the root-knot nematodes, disrupting their structure and causing a leakage of fundamental cellular substances (lysis). When the cell membrane is disrupted, the terpenes disrupt the mitochondria. They no longer function properly and cannot generate energy for the organism due to depletion of the adenosine triphosphate (ATP), the primary cellular energy-transfer carrier. This ultimately leads to the death of the cell.

The effect of Cedroz on nematode cell membranes

Mitochondria* are membrane-bound organelles found in the cells of most eukaryotic organisms. Named after the Greek words for thread and granule, mitochondria are sometimes referred to as the powerhouse of the cell because they produce most of its energy. Mitochondria facilitate the production of ATP, which is the main source of chemical energy in living organisms. If the cell membrane is damaged, ATP is depleted. Without ATP, many cellular processes cannot occur.


Cedroz - Animal cells

The lethal effect of Cedroz on nematodes

An in vitro test was done to demonstrate the lethal effect of Cedroz on root-knot nematodes (Meloidogyne). Watch the following video to find out more.


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